Dense connective tissue, the kind tendons are made of, under a microscope. Illustration only; not from a study in our guides. Echinaceapallida, CC BY-SA 4.0, edited.
Best means best evidence, not safe or right for you. A peptide shown to help in controlled human trials ranks above one tested only in animals, whatever the marketing says. Any commercial relationship is disclosed next to the content it touches.
Human trialsControlled trials in people, published in a journal, that tested a clinical outcome and showed a benefit. The strongest kind of evidence we report.
Limited human dataSmall, short or inconclusive human studies, including observational studies, uncontrolled trials and controlled trials that did not show a clinical benefit.
Animal studiesResults in animals often don’t carry over to people.
Lab studiesCells or tissue in a dish. An early signal, not an answer.
Bremelanotide (Vyleesi) is FDA-approved only for premenopausal women with acquired, generalized HSDD. What trials showed, the risks and what isn't proven.
Tesamorelin (Egrifta) is FDA-approved to reduce abdominal fat in adults with HIV and lipodystrophy only. What the trials show, risks and what isn't proven.
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